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The workforce focused on blocking a protein known as synaptotagmin-two, or Syt2. Syt2 is discovered over the surface area on the granules containing mucin. Fusion of those granules with the cell membrane depends on Syt2 interacting with proteins in the cell membrane.
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Perform by others, which include Dickey, has proven that upsized mucin secretion within the airways is effective in Considerably the identical way, involving analogous vesicles (filled with mucin in place of neurotransmitters) and synaptotagmin and collaborating proteins.
Following time you’re sneezing your brains out or coughing up a lung, take into consideration that lungs and brains have a little something a great deal in popular: Secretion in both equally organs operates similarly.
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Stanford Drugs investigators as well as their collaborators have developed a compound that’s uniquely able to blocking abnormal mucus secretion — an indicator of several significant respiratory Issues. March 23, 2022 - By Bruce Goldman
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